Dr Tony Clarke completed his undergraduate training at the University of Cape Town Medical School in 1970, and completed his Internship at Groote Schuur Hospital. The following two years were spent in Rhodesia, now Zimbabwe, in Mpilo Hospital. In 1974, Dr Clarke gained membership to the Royal College of Physicians of London.

In 1975 Dr Clarke migrated to New Zealand, where he undertook his advance training in Gastroenterology at Auckland Hospital and received Fellowship of the Royal Australasian College of Physicians in 1978. In 1978 Tony took up an appointment in Canberra at the (then) Woden Valley Hospital as a staff gastroenterologist. In 1982 he founded Medical Specialists Associated, now gastrotrACT.

He has significant experience in managing all gastroenterological problems but his particular expertise is in performing the more highly specialised endoscopic procedures - ERCP and other therapeutic manoeuvres.

Dr Clarke has served on many committees and boards involving healthcare in the ACT and nationally. He is a Senior Lecturer at the Australian National University Medical School.